Volume 41, Issue 7 p. 1145-1148
Case Report

Uterine cervical cancer with brain metastasis as the initial site of presentation

Yumi Sato

Yumi Sato

Department of Obstetrics and Gynecology, Kyorin University School of Medicine, Mitaka, Tokyo, Japan

Search for more papers by this author
Kei Tanaka

Kei Tanaka

Department of Obstetrics and Gynecology, Kyorin University School of Medicine, Mitaka, Tokyo, Japan

Search for more papers by this author
Yoichi Kobayashi

Corresponding Author

Yoichi Kobayashi

Department of Obstetrics and Gynecology, Kyorin University School of Medicine, Mitaka, Tokyo, Japan

Reprint request to: Dr Yoichi Kobayashi, Department of Obstetrics and Gynecology, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka, Tokyo 181-8611, Japan. Email: [email protected]Search for more papers by this author
Hiromi Shibuya

Hiromi Shibuya

Department of Obstetrics and Gynecology, Kyorin University School of Medicine, Mitaka, Tokyo, Japan

Search for more papers by this author
Yoshiko Nishigaya

Yoshiko Nishigaya

Department of Obstetrics and Gynecology, Kyorin University School of Medicine, Mitaka, Tokyo, Japan

Search for more papers by this author
Mai Momomura

Mai Momomura

Department of Obstetrics and Gynecology, Kyorin University School of Medicine, Mitaka, Tokyo, Japan

Search for more papers by this author
Hironori Matsumoto

Hironori Matsumoto

Department of Obstetrics and Gynecology, Kyorin University School of Medicine, Mitaka, Tokyo, Japan

Search for more papers by this author
Mitsutoshi Iwashita

Mitsutoshi Iwashita

Department of Obstetrics and Gynecology, Kyorin University School of Medicine, Mitaka, Tokyo, Japan

Search for more papers by this author
First published: 06 February 2015
Citations: 7

Abstract

Brain metastasis from uterine cervical cancer is rare, with an incidence of 0.5%, and usually occurs late in the course of the disease. We report a case of uterine cervical cancer with brain metastasis as the initial site of presentation. A 50-year-old woman with headache, vertigo, amnesia and loss of appetite was admitted for persistent vomiting. Contrast enhanced computed tomography showed a solitary right frontal cerebral lesion with ring enhancement and uterine cervical tumor. She was diagnosed with uterine cervical squamous cell carcinoma with parametrium invasion and no other distant affected organs were detected. The cerebral lesion was surgically removed and pathologically proved to be metastasis of uterine cervical squamous cell carcinoma. The patient underwent concurrent chemoradiotherapy, followed by cerebral radiation therapy, but multiple metastases to the liver and lung developed and the patient died 7 months after diagnosis of brain metastasis.