Volume 40, Issue 2 p. 165-172

Patterns of medication use during and prior to pregnancy: the M A P study

Amanda Henry

Amanda Henry

Department of Obstetrics and Gynaecology, The University of Adelaide, Women's and Children's Hospital, Adelaide, South Australia

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Caroline Crowther

Corresponding Author

Caroline Crowther

Department of Obstetrics and Gynaecology, The University of Adelaide, Women's and Children's Hospital, Adelaide, South Australia

5 Department of Obstetrics and Gynaecology The University of Adelaide Women's and Children's Hospital King William Road North Adelaide South Australia 5006 Australia1Search for more papers by this author
First published: 13 February 2008
Citations: 58

Abstract

Summary: We interviewed 140 pregnant women of any gestational age attending antenatal clinics at the Women's and Children's Hospital in Adelaide during September-October 1999 to elicit information about their patterns of medication use during and in the 3 months prior to their current pregnancy.

Demographic information, information on women's prescribed, non-prescribed, and non-medicinal drug use during and in the 3 months prior to pregnancy, and information about both their general sources of information on medication use and their specific reasons for medication uptake/cessation during pregnancy were obtained.

The women used an average of 0.7-0.8 prescribed and 2.3-2.6 non-prescribed medications (total 3.1–3.3) in the 3 pregnancy trimesters, compared with 1.0 prescribed and 2.2 non-prescribed prior to pregnancy. Use of a prescribed or non-prescribed medication was 96–97% across trimesters.

Simple analgesics, vitamin/mineral supplements, and antacids were the most commonly taken medications. Antibiotics were the most commonly prescribed medication. Use of class A medications increased during pregnancy while use of non-class A medications decreased. Peri-conceptional folate supplementation was 31%.

Alcohol consumption and cigarette smoking decreased after diagnosis of pregnancy. Both prescribed and non-prescribed medication use is common during all trimesters of pregnancy However, overall use changes little compared with pre-pregnancy values. Rates of peri-conceptional folate supplementation are low.