Volume 87, Issue 3 p. 220-226
Articles

Risk factors and obstetric complications associated with macrosomia

N.E. Stotland

Corresponding Author

N.E. Stotland

Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, CA, USA

Corresponding author. San Francisco General Hospital, Ward 6D-1, 1001 Potrero Avenue, San Francisco, CA 94110, United States. Tel.: +1 415 206 3642; fax: +1 415 206 3112.Search for more papers by this author
A.B. Caughey

A.B. Caughey

Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, CA, USA

Department of Health Services and Policy Analysis, University of California, Berkeley, CA, USA

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E.M. Breed

E.M. Breed

Perinatal Research Unit, Kaiser Permanente Division of Research, Walnut Creek, CA, USA

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G.J. Escobar

G.J. Escobar

Perinatal Research Unit, Kaiser Permanente Division of Research, Walnut Creek, CA, USA

Department of Pediatrics, Kaiser Permanente Medical Center, Walnut Creek, CA, USA

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First published: 07 October 2004
Citations: 201

Abstract

Objective

Macrosomia is associated with adverse maternal outcomes. The objective of this study was to characterize the epidemiology of macrosomia and related maternal complications.

Method

Live births (146,526) were identified between 1995 and 1999 in the Kaiser Permanente Medical Care Program's Northern California Region (KPMCP NCR) database. Bivariate and multivariate analyses were performed for risk factors and complications associated with macrosomia (birth weight >4500 g).

Result

Male infant sex, multiparity, maternal age 30–40, white race, diabetes, and gestational age >41 weeks were associated with macrosomia (p<0.001). In bivariate and multivariate analyses, macrosomia was associated with higher rates of cesarean birth, chorioamnionitis, shoulder dystocia, fourth-degree perineal lacerations, postpartum hemorrhage, and prolonged hospital stay (p<0.01).

Conclusion

Macrosomia was associated with adverse maternal outcomes in this cohort. More research is needed to determine how to prevent complications related to excessive birth weight.