Volume 148, Issue 2 p. 210-218
CLINICAL ARTICLE

Trends and predictors of gestational diabetes mellitus in Chile

María L. Garmendia

Corresponding Author

María L. Garmendia

Institute of Nutrition and Food Technology, University of Chile, Santiago, Chile

Correspondence

María L. Garmendia, Institute of Nutrition and Food Technology, El Líbano, Santiago, Chile.

Email: [email protected]

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Susana Mondschein

Susana Mondschein

School of Engineering and Sciences, Adolfo Ibáñez University, Santiago, Chile

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Braulio Montiel

Braulio Montiel

School of Engineering and Sciences, Adolfo Ibáñez University, Santiago, Chile

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Juan P. Kusanovic

Juan P. Kusanovic

High Risk Pregnancy Unit, Center for Research and Innovation in Maternal-Fetal Medicine (CIMAF), Hospital Dr. Sótero del Río, Santiago, Chile

Division of Obstetrics and Gynecology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile

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First published: 31 October 2019
Citations: 22

Abstract

Objective

To examine the temporal trends in gestational diabetes mellitus (GDM) prevalence in Chile, and to determine the main predictors of GDM.

Methods

A secondary analysis was conducted of all birth records at Hospital Dr. Sótero del Río, Chile, from January 1, 2002, to December 31, 2015. We excluded those women with pre-existing type 2 diabetes, those with missing data, and those with unlikely data. GDM was defined as fasting glucose levels >5.55 mmol/L [>100 mg/dL] or >7.77 mmol/L [>140 mg/dL] 2 hours after glucose load in the oral glucose tolerance test. Potential predictors were selected based on prior research and ease of evaluation.

Results

From the original database of 100 758 records, 86 362 women were included in the final cohort. The mean GDM prevalence was 7.6% (95% CI [confidence interval] 7.5%–7.8%), increasing from 4.4% (95% CI 4.0%–4.9%) in 2002 to 13.0% (95% CI 12.0%–13.9%) in 2015. Age, education, marital status, parity, family history of type 2 diabetes, personal history of GDM, hypertension and pre-eclampsia, alcohol consumption, smoking, and pre-gestational nutritional status performed well in the prediction of GDM.

Conclusion

One out of eight Chilean pregnant women of medium- to low socio-economic status were found to develop GDM. We identified a set of easy-to-capture predictors in the primary health care system that may allow for the early identification of women at high-risk for the development of GDM.

CONFLICTS OF INTEREST

The authors have no conflicts of interest.